Stanford Center for Inherited Cardiovascular Disease

Marfan Syndrome and Aortic Disorders

Contact Information

Stanford University Medical Center
Cardiology Clinic, 2nd Floor of Main Hospital
300 Pasteur Drive, Room H2157, Stanford, CA 94305-5233
Driving directions

New/Return Patients
(650) 725-8246

(650) 724-4034

E-mail [spellone]

Clinic Hours
Monday - Friday 8:30am-5:30pm

The Stanford University Center for Marfan Syndrome and Aortic Disorders is the largest of its kind in California and among the nation's leading centers for the diagnosis and treatment of Marfan syndrome. At Stanford Hospital, the center is multidisciplinary, ensuring that patients with Marfan syndrome and aortic disorders have access to comprehensive diagnostic and management services from specialists in cardiology, cardiovascular surgery, ophthalmology, orthopedics and genetics. Genetic molecular research is taking place to identify genetic changes believed to be related to Marfan syndrome and other inherited aortic disorders. We are also researching new treatments that could potentially eliminate the development of vascular complications and decrease the need for operative interventions in our patients.

Marfan syndrome is a genetic disorder of connective tissue disorder that can affect the heart, blood vessels, lungs, eyes, bones and ligaments. In Marfan syndrome, the protein necessary for strengthening the connective tissue, fibrillin 1, does not work properly, affecting the growth and development of the body.

Approximately one in every 5,000 people worldwide is diagnosed with Marfan syndrome. That's approximately 200,000 men, women and children of every race and ethnic group in the United States.  Prior to innovations in the medical and surgical management of this disease, most patients died of cardiovascular complications by age 50. The Stanford University Marfan Center was established in 1988 by Dr. D. Craig Miller at the urging of the local chapter of the National Marfan Foundation. Through our multidisciplinary approach, patients with MFS now have a normal life expectancy.

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